Plant-Based Recombinant Protein Production Platform

Plant-produced recombinant proteins provide a sustainable and cost-effective alternative to traditional protein manufacturing methods. SignalChem leverages the potential of plants as bioreactors to optimize protein expression and recovery. Plants offer unique advantages, including their innate inability to cause human diseases, making them ideal for producing orally administered antigens.

SignalChem employs strategic methods for recombinant protein production, including:

• Cell-Culture-Based Systems: Controlled environments to enhance protein synthesis.
• Transient Expression in Plant leaves: Utilizing agroinfiltration to achieve high-yield protein production.

These innovative approaches harness the full potential of plant-based systems, enabling robust and scalable production of recombinant proteins. This platform opens new avenues for applications in biotechnology and medicine.

Innovative Bio-Stimulant-Based Platform

SignalChem Plantech utilizes genomic insights to enhance the nutritional value of produce, herbs, and supplements through non-transgenic methods. Central to this effort is the development of an innovative bio-stimulant-based platform designed to amplify bioactive compounds in fruits, vegetables, and medicinal plants such as Chinese traditional herbs (TCM).

Key benefits and features include:

• Bio-Stimulant Action: Enhancing plants’ natural processes to improve nutrient uptake and stress tolerance sustainably.
• Secondary Metabolite Synthesis: Utilizing elicitors to trigger signaling pathways, boosting the production of health-promoting elements.

This platform represents a sustainable agricultural solution, minimizing environmental impacts while reshaping possibilities in nutrition and therapy.

Plant-Based Drug Discovery & Development Platform

SignalChem Plantech integrates its parent company’s advanced platform to conduct high-throughput screening of bioactive natural compounds. The primary focus lies in identifying and developing target-specific molecule clusters and individual molecules from medicinal plants.

Innovative Techniques and Applications:

• Affinity Ultrafiltration Techniques (UF-LC-MS): Expediting the identification and development of promising drug candidates.
• Focus Areas: Developing treatments for metabolic disorders, including diabetes, obesity, hyperuricemia, and NAFLD/NASH (non-alcoholic fatty liver disease/non-alcoholic steatohepatitis).

SignalChem’s efforts are geared toward pioneering drug targets and therapeutic approaches. By targeting fundamental mechanisms and contributing factors of metabolic disorders, the platform aims to revolutionize their management, treatment, and prevention.

Plant secondary metabolite analysis and identification

Global Natural Product Social Molecular Networking (GNPS) is an interactive online small molecule–focused tandem mass spectrometry (MS2) data curation and analysis infrastructure. Molecular networking—one of the main analysis tools used within the GNPS platform—creates a structured data table that reflects the molecular diversity captured in tandem mass spectrometry experiments by computing the relationships of the MS2 spectra as spectral similarity. This protocol provides step-by-step instructions for creating reproducible, high-quality molecular networks. This technique can be used to identify associated with bioactive compounds in combination, are likely to develop great originality of new drugs. By integrating chemical composition analysis, bioactivity analysis and bioinformatics, we identified possible active ingredient combinations in complex components in a goal-oriented way by predicting, separating and verifying the active ingredients.

Provide third-party analytic testing, contract research and consulting services that enable our clients to develop, manufacture and market high quality, efficacious botanical supplements and food products for human and animal nutrition.